Richard Robitaille (Université de Montréal • Montréal, Canada)
Ca²⁺ imaging tools: modes of action and limitations
[25 min + 10 min discussion]

Alfonso Araque (University of Minnesota • Minneapolis, MN, USA)
Stimulating neurons and astrocytes
[25 min + 10 min discussion]

Coffee break

Marta Navarette (Cahal Institute • Madrid, Spain)
Innovative tools to unravel astrocyte contributions to behavior
[25 min + 10 min discussion]

Student presentations

[7 min + 3 min discussion each]

Eva Breuer (Hannover, Germany)
Shaping brain function: how astrocyte morphology and signaling refine astrocyte-neuron communication

Javier Sánchez Romero (Madrid, Spain)
An astrocyte ensemble modulates synaptic communication in the medial prefrontal cortex-nucleus accumbens circuit

Antonin Singer (Homburg, Germany)
Electrophysiological analysis of glial adrenergic signaling in spinal nociceptive circuits

Marta González Martín (Madrid, Spain)
Astrocyte plasticity in the anterior cingulate cortex: implications for voluntary behavior regulation

Giorgio Letti (Genoa, Italy)
Do astrocytic calcium signals display allocentric head-direction tuning in the hippocampus of freely moving mice?

Agora • Info & Preparation (1)

Lunch

Student presentations

[7 min + 3 min discussion each]

Cristina Boers Escuder (Amsterdam, The Netherlands)
Deletion of astrocytic intermediate filaments GFAP and Vimentin enhances protein synthesis and prevents early synaptic and cognitive dysfunction in a mouse model of Alzheimer’s disease

Gonzalo Blasco (Amsterdam, The Netherlands)
Proteomic profiling of astrocyte reactivity in hiPSC-derived models as a tool for translational biomarker studies in neurodegenerative diseases

Danielle Arbour (Montréal, Canada)
Glial cell covering at the human neuromuscular junction is associated with the altered locomotor capacity in aging

Shuai Wang (Dublin, Ireland)
Could von willebrand factor-astrocyte interactions contribute to stroke injury?

Hind Ibork (Bordeaux, France)
From astrocytes to tumor cells: the role of the mtCB1 receptor in glioblastoma

Francesca Postogna (Milan, Italy)
Cholesterol deregulation in Rett syndrome: implications for synaptic functions

Frank Kirchhoff (University of Saarland • Homburg, Germany)
Genetic models to study astrocyte functions - the pros and cons of various transgenic mouse models
[25 min + 10 min discussion]

Coffee break

Keith Murai (McGill University Health Centre • Montréal, Canada)
Targeting astrocytes: labeling approaches for astrocyte visualization and molecular manipulation
[25 min + 10 min discussion]

Student presentations

[7 min + 3 min discussion each]

Jake Miller (College Park, MD, USA)
The contribution of astrocytic dynamics to energy-constrained image recognition learning

Chen Schieber (Jerusalem , Israel)
Astrocytes encode reward in non-spatial environments

Josephine Wilkes (Amsterdam, The Netherlands)
Optimisation of recombinant adeno-assoicated virus (rAAV) vectors for astrocyte transduction to deliver CRISPR components to edit the astrocyte APOE4 gene to neuroprotective APOE4 Christchurch R136S variant in the development of more effective Alzheimer disease treatments

Jeanne Cueille (Strasbourg, France)
Investigation of oxytocin signaling in amygdala astrocytes and its impact on behavioral responses to stress

Erica Pedron (Bern, Switzerland)
Astrocytic network dynamics are different between cortical areas during sleep-wake states and during sleep homeostatic processes

Fiorella Mancini (Benevento, Italy)
Study of the mechanisms regulating blood-brain barrier integrity in inflammatory conditions

Dinner

Student presentations

[7 min + 3 min discussion each]

Larissa Andrade (Ribeirão Preto, Brazil)
Astrocytic PKM2 acts as a metabolic break on the development of neuroinflammation

Lea Dennaoui (Lausanne, Switzerland)
Microglia influence astrocyte maturation in the developing hippocampus

Mia Till (Victoria, Canada)
Prenatal tetrahydrocannabinol exposure results in regional differences in neuroinflammation in the rat hippocampus

Max-Michael de Jongh (Amsterdam, The Netherlands)
Investigating the role of astrocyte endfeet proteins and their interaction with the blood-brain-barrier in a gliovascular unit on a chip

Nicole Tonesi (Padua, Italy)
Characterization of cerebral vascularization and gliovascular interface in the B6.152H mouse model of familial Alzheimer’s disease

Mriganka Sur (Massachusetts Institute of Technology • Cambridge, MA, USA)
Norepinephrine-driven extended calcium signaling in cortical astrocytes is essential for learned behavior
[25 min + 10 min discussion]

Coffee break

Student presentations

[7 min + 3 min discussion each]

Rodrigo Díaz Muñoz (Ciudad Real, Spain)
Astrocytic reactivity in male and female mice of an early amyloidosis model

Edson dos Santos Silva (São Paulo, Brazil)
Sympathetic nervous system–driven β2-adrenergic signaling modulates astrocyte neuroinflammation and metabolism in a microglia-induced neuroinflammatory model

Nilma do Rocio Janisset (São Paulo, Brazil)
Neurobiological alterations and neuroinflammatory effects of cocaine exposure in primary cultures of astrocytes and microglia

Alicja Mejza (Wrocław, Poland)
CRISPR-Cas9 functional analysis of α2,6-sialylation in astrocyte and microglial responses to immunostimulants

Nadia Mirza-Romero (Boston, MA, USA)
Murine astrocytes display differential susceptibility to prion strains

Rosa C. Paolicelli (University of Lausanne • Lausanne, Switzerland)
The relevance of functional assays to understand microglial complexity
[25 min + 10 min discussion]

Lunch

Cristina García Cáceres (Ludwig-Maximilians-Universität • Neuherberg, Germany)
Applied neuroscience metabolic methods to investigate the coupling of astrocyte-neuron interactions in the control of systemic metabolism
[25 min + 10 min discussion]

Agora • Preparation (2) [with coffee]
Students divided in groups

Pizza party

João Oliveira (University of Minho • Braga, Portugal)
Behavioral testing: the devil is in the details
[25 min + 10 min discussion]

Elly Hol (UMC Utrecht • Utrecht, The Netherlands)
Human astrocytes: from post-mortem brains to iPSC models
[25 min + 10 min discussion]

Coffee break

Alfonso Araque (University of Minnesota • Minneapolis, MN, USA)
Scaling up tripartite synapses: from synapses to network and behavior
[25 min + 10 min discussion]

Mriganka Sur (Massachusetts Institute of Technology • Cambridge, MA, USA)
Astrocyte glutamate and GABA transporters critically regulate vascular dynamics and neuronal information coding
[25 min + 10 min discussion]

Lunch

Departure to Ravenna
Sightseeing and guided tours, followed by dinner
Return to Bertinoro after dinner

João Oliveira (University of Minho • Braga, Portugal)
Astrocytes modulate cortico-limbic circuit function and behavior
[25 min + 10 min discussion]

Marta Navarette (Cahal Institute • Madrid, Spain)
Decoding memory traces: the role of astrocyte ensembles
[25 min + 10 min discussion]

Coffee break

Frank Kirchhoff (University of Saarland • Homburg, Germany)
Functional analysis of astrocytes and other glial cells reveals relevant sex-specific differences
[25 min + 10 min discussion]

Keith Murai ((McGill University Health Centre • Montréal, Canada)
Molecular and structural signatures of astrocytes in CNS health and disease
[25 min + 10 min discussion]

Lunch

Giorgio Carmignoto (CNR Institute of Neurosciences • Padua, Italy)
Spontaneous calcium events in astrocytes are stochastic functional signals in the brain
[30 min + 10 min discussion]

Agora • Preparation (3) [with coffee]
Students divided in groups

Dinner

Rosa C. Paolicelli (University of Lausanne • Lausanne, Switzerland)
Microglia across the lifespan: from brain maturation to neurodegeneration
[25 min + 10 min discussion]

Elly Hol (UMC Utrecht • Utrecht, The Netherlands)
The astrocyte cytoskeleton in disease
[25 min + 10 min discussion]

Coffee break

Cristina García Cáceres (Ludwig-Maximilians-Universität • Neuherberg, Germany)
Hypothalamic astrocytes integrate timing and metabolic cues to control feeding circuits
[25 min + 10 min discussion]

Richard Robitaille (Université de Montréal • Montréal, Canada)
Glial cells regulate neuromuscular junction in health and disease
[25 min + 10 min discussion]

Lunch

Agora presentations [with coffee]

General discussion, Concluding Remarks, Questionnaires

Farewell Dinner